The battle of Cynoscephalae represents a key moment in the history of the Greco-Roman world. In this one battle the Macedonian hold over mainland Greece was broken, with the Roman Republic rising in its place as the pre-eminent power in the Greek East. At Cynoscephalae, the proud Macedonian kingdom of Antigonid monarch Philip V was humbled, its army shattered. Yet the battle, and campaign leading up to it, was hard fought and protracted. Philip V had defied Rome and its allies in the First Macedonian War and was poised to do so again, with the pike phalanx continuing to be a daunting opponent for the Roman legionaries.

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