Ketamine has a complicated reputation. It’s been a horse tranquilizer, a party drug, linked to celebrity headlines, and is now being explored as a breakthrough treatment for depression, PTSD, and trauma. So what is it really?

Dr. Priyanka and Hari trace ketamine’s history from operating rooms to mental health clinics, explain how it works differently from traditional antidepressants, and unpack why it can help some people with treatment-resistant depression. They also discuss the principles of ketamine-assisted psychotherapy (KAP), the lessons from Matthew Perry’s death, and why proper medical oversight matters. Along the way, Dr. Wali shares powerful stories from her own clinical experience.

Ketamine has a complicated reputation. It&rsquo;s been a horse tranquilizer, a party drug, linked to celebrity headlines, and is now being explored as a breakthrough treatment for depression, PTSD, and trauma. So what is it really? Dr. Priyanka and Hari trace ketamine&rsquo;s history from operating rooms to mental health clinics, explain how it works differently from traditional antidepressants, and unpack why it can help some people with treatment-resistant depression. They also discuss the principles of ketamine-assisted psychotherapy (KAP), the lessons from Matthew Perry&rsquo;s death, and why proper medical oversight matters. Along the way, Dr. Wali shares powerful stories from her own clinical experience.

On Health Stuff, hosts Dr. Priyanka Wali and comedian Hari Kondabolu tackle all the health questions that keep you up at night with hilarity and humanity. Together they demystify the flashy trends, and keep you informed on the latest research. You can rely on Health Stuff to bring you real, uninhibited, and thoughtful health talk of the highest caliber, and a healthy dose of humor.

On Health&nbsp;Stuff, hosts Dr. Priyanka Wali and comedian Hari Kondabolu tackle all the health questions that keep you up at night with hilarity and humanity. Together they demystify the flashy trends, and keep you informed on the latest research. You can rely on&nbsp;Health&nbsp;Stuff&nbsp;to bring you real, uninhibited, and thoughtful&nbsp;health&nbsp;talk of the highest caliber, and a healthy dose of humor.

Health Stuff

Ketamine: From Horse Tranquilizer to Mental Health Breakthrough

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/1704e59e-f16a-4b46-ad02-b4950147b48f/transcript