In this episode of Eureka!, a McKinsey podcast on innovation in life sciences R&D, hosts Navraj Nagra, Alex Devereson, and Meredith Langstaff speak to Ashita Batavia, head of hematology and oncology data sciences, R&D, at Johnson & Johnson Innovative Medicine (J&J). They discuss how real-world data can better inform clinical trials, the shifts in mindsets and capabilities needed to support AI in biopharma, and how to navigate the complexity of clinical trials with more-pragmatic trial designs.