What if you could actually delay the process of aging? Dr. Nir Barzilai hopes to identify interventions that could do just that. He believes a class of drugs known as gerotherapeutics could be real game changers.

Dr. Barzilai walks us through his pioneering research and explains why your biological age may actually be different from your chronological age. And we break down the buzziest trends in the longevity space.

Links to resources mentioned in this episode:

Cellergy Therapeutics

How to measure biological aging in humans

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

An Updated Prioritization of Geroscience- Guided FDA-Approved Drugs Repurposed to Target Aging

Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation

The Super Ager Family Study

Nir Barziliai, MD, on what we can learn about longevity from SuperAgers and Centenarians

Cardiovascular advantages among the offspring of centenarians 

Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring

Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring

What You Should Know About NAD+ Supplements

Abstract 4168: NMN supplementation enhances proliferation and aggressiveness in UV-induced skin cancer

Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

What if you could actually delay the process of aging? Dr. Nir Barzilai hopes to identify interventions that could do just that. He believes a class of drugs known as gerotherapeutics could be real game changers.
Dr. Barzilai walks us through his pioneering research and explains why your biological age may actually be different from your chronological age. And we break down the buzziest trends in the longevity space.
Links to resources mentioned in this episode:
<a href="https://www.cellergy-bio.com/">Cellergy Therapeutics</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/40011691/">How to measure biological aging in humans</a>
<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3021372/">Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice</a>
<a href="https://www.researchgate.net/publication/378689495_An_Updated_Prioritization_of_Geroscience-_Guided_FDA-Approved_Drugs_Repurposed_to_Target_Aging">An Updated Prioritization of Geroscience- Guided FDA-Approved Drugs Repurposed to Target Aging</a>
<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12223363/?utm_source=chatgpt.com">Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation</a>
<a href="https://www.superagersstudy.org/">The Super Ager Family Study</a>
<a href="https://www.afar.org/ask-the-expert/nir-barziliai-md-on-what-we-can-learn-about-longevity-from-superagers-and-centenarians">Nir Barziliai, MD, on what we can learn about longevity from SuperAgers and Centenarians</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/12730251/">Cardiovascular advantages among the offspring of centenarians</a>&nbsp;
<a href="https://pubmed.ncbi.nlm.nih.gov/15571545/">Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring</a>
<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6298187/">Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring</a>
<a href="https://www.atria.org/education/nad-supplements/">What You Should Know About NAD+ Supplements</a>
<a href="https://aacrjournals.org/cancerres/article/85/8_Supplement_1/4168/759716/Abstract-4168-NMN-supplementation-enhances">Abstract 4168: NMN supplementation enhances proliferation and aggressiveness in UV-induced skin cancer</a>
Note: In this show, we use &ldquo;women&rdquo; as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

Why is it still so hard for women to find reliable, modern health information about their own bodies? On Decoding Women's Health, Dr. Elizabeth Poynor, chair of women’s health & gynecology at the Atria Health Institute, shares expert insights on women’s health, hormones, and longevity science to help you thrive at any stage of midlife and beyond.

Dr. Poynor, a world-renowned gynecologic oncologist and advanced pelvic surgeon, speaks with leading physicians, researchers, and educators to share the latest science on women’s wellness, disease prevention, and what it really means to age on your own terms. Each episode explores a different aspect of how to improve your health during midlife—from heart disease and genetic risks to metabolism, hormones nutrition, cognitive health, and beyond.

Whether you're in perimenopause, postmenopause, or simply looking for tools to prepare for the next chapter, take charge of your health—now and for the future—with expert guidance and practical advice to help you thrive. 

Why is it still so hard for women to find reliable, modern health information about their own bodies? On Decoding Women's Health, Dr. Elizabeth Poynor, chair of women&rsquo;s health &amp; gynecology at the Atria Health Institute, shares expert insights on women&rsquo;s health, hormones, and longevity science to help you thrive at any stage of midlife and beyond.
Dr. Poynor, a world-renowned gynecologic oncologist and advanced pelvic surgeon, speaks with leading physicians, researchers, and educators to share the latest science on women&rsquo;s wellness, disease prevention, and what it really means to age on your own terms. Each episode explores a different aspect of how to improve your health during midlife&mdash;from heart disease and genetic risks to metabolism, hormones nutrition, cognitive health, and beyond.
Whether you're in perimenopause, postmenopause, or simply looking for tools to prepare for the next chapter, take charge of your health&mdash;now and for the future&mdash;with expert guidance and practical advice to help you thrive.&nbsp;

Decoding Women's Health with Dr. Elizabeth Poynor

Decoding Longevity with Dr. Nir Barzilai

https://api.omny.fm/orgs/e73c998e-6e60-432f-8610-ae210140c5b1/clips/9088f364-ef98-408d-8ff0-b424017bc75b/transcript