Bloomberg News Health Care Reporter Robert Langreth discusses news that the first confirmed U.S. case of the omicron variant was detected in California according to the CDC. Bloomberg News Venture Capital Reporter Lizette Chapman explains how U.S. Crypto startups are overtaking China and the rest of Asia in VC deals. Bloomberg Businessweek Editor Joel Weber and Businessweek Features Editor Bret Begun talk about The Bloomberg 50, the people who defined global business in 2021. Wall Street Journal Technology Columnist Christopher Mims discusses his book "Arriving Today: From Factory to Front Door- Why Everything Has Changed About How and What We Buy." And We Drive to the Close with Dan Pipitone, Co-Founder of TradeZero America.

Hosts: Carol Massar and Tim Stenovec. Producer: Paul Brennan.