The guys discuss Brian Daboll leaving the Bills to become head coach of the NY Giants and the relationship between new Bills offensive coordinator Ken Dorsey and quarterback Josh Allen. Also, a Super Bowl LVI preview with our favorite prop bets and menu items. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys break down the Bills’ devastating loss to the Chiefs in the Divisional Round of the AFC playoffs. Topics include how head coach Sean McDermott and the Bills handled the final 13 seconds of regulation, Josh Allen’s legendary performance and takes on the NFL’s overtime rules in the playoffs. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys break down the Bills’ epic playoff win over the Patriots and look ahead to their Divisional Round matchup with the Chiefs. Topics include analytics loving the Bills as Super Bowl favorites and a Bills-Chiefs betting preview with picks against the spread and total. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss Bills-Patriots Round III, this time on wild-card weekend. Topics include punter Matt Haack and the Bills’ not-so-special teams, the team’s new winning combo along the offensive line and a Bills-Pats preview with predictions against the spread and total. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys break down the Bills’ sloppy win over the Falcons in snowy Buffalo. Could bad weather (not talent or coaching) be the team’s ultimate downfall in the playoffs? Other topics include resetting where the Bills sit in the latest Touchdown Wire power rankings; Marquez Stevenson vs. Isaiah McKenzie as the team’s primary punt returner; and a Bills-Jets betting preview with predictions. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys break down Buffalo’s wire-to-wire win over the Patriots in Foxboro, including how Sean McDermott responded to Bill Belichick with the perfect game plan. Was this the best performance in Josh Allen’s career? Also, a look ahead to what’s next for the Bills, including potential playoff matchups, and a Bills-Falcons betting preview with picks against the spread and total. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys open up by discussing Bills-Patriots Round 2. If the Patriots go with more heavy personnel on offense, will the Bills match them this time to compete in the run game? Topics include “the blueprint” to beat the Patriots, Devin Singletary’s recent surge and a Bills-Patriots preview with picks against the spread. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys break down the Bills’ tough, overtime loss to Tampa Bay and look ahead to the team’s final four games of the regular season. Should we buy or sell the Bills as AFC playoff contenders? Other topics include Gabe Davis’ rising stock for the fantasy football playoffs, Sean McDermott’s late-game coaching decisions and a Bills-Panthers preview with picks against the spread and total. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss Buffalo’s brutal loss to the Patriots, weighing in on roster construction, game planning and in-game coaching decisions. Also, a Bills-Bucs preview with picks against the spread. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys dive into this week’s Monday Night Football showdown between the Bills and the Patriots, and give their predictions against the spread and moneyline. Also, thoughts on the Bills’ Thanksgiving night rout of the Saints, Tre White's season-ending knee injury and how the secondary could look moving forward. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

Host Ryan O’Leary is on his way to Buffalo to take in the Bills-Colts game as a fan, so Bills Wire Managing Editor Nick Wojton offers some advice on how visiting football fans can get the perfect Bills game weekend experience, from places to check out on Saturday night to the best tailgating areas on Sunday. The guys also react to the Bills’ blowout win over the Jets and offer up a Bills-Colts preview with picks against the spread and total.

The guys try to piece together how the Bills actually got beat by the Jaguars and reset their thoughts on the current AFC playoff picture. Could the Bills’ dud in Jacksonville actually cost them the AFC’s No. 1 seed? Also, a Bills-Jets preview with picks against the spread. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss whether folks should be impressed with Sunday’s grind-it-out win over Miami and look ahead to another double-digit spread against the Jaguars. Also, did the Bills miss an opportunity to trade for Von Miller? Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss the Bills’ standing in what is now a wide-open AFC playoff race. Topics include the NFL trade deadline and a Bills-Dolphins preview with picks against the spread. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

Steve Borstein fills in for Ryan O'Leary in this week's Bills Wire Podcast, discussing this week's Monday night performance.

The guys look ahead to one of the game’s of the young 2021 season: Bills vs. Chiefs in Kansas City. Are the Bills primed to beat the Chiefs and stake their claim as the best team in the conference? Also, how to approach Dawson Knox in fantasy football leagues and Bills-Chiefs sports betting angles and predictions. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton).

The guys discuss Josh Allen’s massive bounce-back performance, Emmanuel Sanders’ instant impact and more on the team’s blowout win over Washington. Also, why the Bills’ defense is for real entering a huge Week 5 showdown in Kansas City. But first things first, the guys give their thoughts on the Bills-Texans matchup and whether they’re backing the Bills as a 16.5-point favorite. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss the Bills’ Week 2 beatdown of the Dolphins and look ahead to their upcoming matchup with the Washington Football Team. Topics include the team’s hot start on defense and whether Josh Allen is the buy-low candidate of the year in fantasy football after his slow start statistically. The guys also take a look at the Bills-Washington betting lines and make their picks. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss the Bills’ Week 1 disaster against the Steelers and look ahead to this week’s game in Miami. Topics include the team’s offensive line struggles, Zack Moss’ surprise benching and some betting trends to know when picking this week’s Bills-Dolphins game. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys refute some hot national media takes on the Bills, discuss the ongoing battle for the two open guard spots on the offensive line and dive into the team’s Week 1 matchup against the Steelers. They also talk sports betting angles and why this might be a smart time to bet the under. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys react to the Bills’ initial 53-man roster, including the team’s decision to move on from recently signed tight end Jacob Hollister. Other topics include the team’s 11 defensive linemen, Gabriel Davis as a fantasy sleeper, and some early picks on the Bills-Steelers Week 1 betting line. Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton)

The guys discuss where the Bills’ stadium negotiations are at and where the team is most likely to end up. (There’s no chance it’s Austin!) Also, the latest on the team’s COVID situation and how soon is too soon to draft Josh Allen in fantasy football? Hosted by Ryan O’Leary (@RyanO_Leary) with Bills Wire Managing Editor Nick Wojton (@Nick_Wojton).

Bills Wire editor Nick Wojton and host Ryan O’Leary return with thoughts on Josh Allen’s new six-year, $258M extension, Cole Beasley’s rants against COVID-19 vaccinations, key preseason position battles and more! Also, has Devin Singletary picked up enough steam to warrant flex appeal in fantasy drafts this season? And is August the best time to bet the Bills at +1000 odds to win the Super Bowl?

The guys wrap up the first big wave of the offseason with takes on where the Bills improved the most and where they still see holes. Also, with few starting spots up for grabs, they take a look at positions like corner, tight end and interior defensive line, and discuss the most interesting player battles entering the summer.

The Bills had a clear strategy for this draft class: Get bigger. Of their first four selections in the 2021 NFL Draft, second-round edge defender Carlos Basham Jr. is the little guy at 6-foot-5, 285 pounds. The guys react to that strategy and the Bills’ new draft class overall. Also, thoughts on the team picking up the fifth-year options on QB Josh Allen and LB Tremaine Edwards. 

Draft Wire editor Luke Easterling, with host Ryan O’Leary, give their final takes on Day 1 of the NFL Draft. Could Micah Parsons tumble to the Steelers at pick No. 24? Are the Patriots poised to make a move for their quarterback of the future? Will Patrick Surtain make it past the top 10 picks after the Broncos’ trade for QB Teddy Bridgewater? Elijah Moore or Alex Leatherwood for the Packers at pick No. 30? Happy draft weekend everybody!

In the first round of the 2019 NFL Draft, the Buffalo Bills selected defensive tackle Ed Oliver out of Houston. If they could do it all over again, would they make the same pick? The guys revisit the Bills’ 2019 draft class and debate what some of those decisions could mean for the team’s plans in the upcoming 2021 version. Another stab at tight end, anyone?

The guys react to some recent comments by Bills director of personnel Dan Morgan, and what that might signal for the team’s approach on Day 1 of the NFL Draft. Also, how fans are reacting to the news of “no COVID vaccine, no entry” to Bills games this season, and what we can glean from sportsbook odds ahead of draft day.

The guys take a mock draft breather and play “Hit or Miss” with the Bills’ seven-player draft class from 2020. Is third-round RB Zack Moss a hit or a miss? Also, some thoughts on this year’s draft. Should the Bills be feeling any added pressure to get this thing right?

With the Jets getting ready to select their next quarterback No. 2 overall, the Dolphins strategically building through the draft, and the Patriots feverishly building through free agency, the Bills suddenly find themselves leading a hot division entering 2021. The guys discuss the state of the AFC East, the latest mock drafts for the Bills at No. 30, and the franchise’s long-winded new stadium name.

The Bills moved on from WR John Brown but quickly filled the void by landing veteran Emmanuel Sanders, formerly of the Saints, on a 1-year deal. The guys react to that and the Bills’ other key moves in free agency, and preview what could be coming next during the second wave of signings.

The Bills spent much of the NFL’s legal tampering period coming to terms with their own key free agents. They’re bringing back Jon Feliciano and Daryl Williams on the offensive line, and also agreed to a long-term deal with LB Matt Milano, who likely would have gotten a bigger payday elsewhere. The guys react to those moves, and look ahead to what could be coming next during the official start of the new league year.

The Bills continue to invest in their secondary, agreeing to a two-year extension with safety Micah Hyde. The guys react to Hyde’s new deal, the team’s decision not to franchise tag LB Matt Milano, and discuss what Dak Prescott’s new monster deal with Dallas means for the soon-to-be-paid Josh Allen.

J.J. Watt to the Bills? It sounded like a perfect fit, didn’t it? The Bills are building a Super Bowl contender. Pass rush is a need. Watt wants to play for a winner. So why would the former Houston Texans star pick … the Arizona Cardinals? In the return of the Bills Wire Podcast for the 2021 season, the guys give their take on Watt and discuss the team’s top areas of need entering the official start of free agency.

There’s plenty of blame to go around for the players and coaches after the Bills were outclassed by Kansas City in the AFC Championship Game. But there’s a clear silver lining: Maybe this Bills team, which has been building momentum in past seasons, arrived ahead of schedule in 2020. The guys vent over some poor play and questionable coaching, but also reflect on a great run that saw the Bills dominate the AFC East and win two playoff games behind Josh Allen’s breakout season. With the core of the team under contract for 2021, a more confident and motivated Bills team is poised to be back contending for years.

The Bills responded against the Ravens, making life miserable for Lamar Jackson thanks to a championship-like performance from the defense. Now comes the real test. The Bills will go on the road and face Patrick Mahomes and the defending Super Bowl champion Chiefs in the AFC Championship Game. For all the steps Josh Allen and these Bills have taken this season, are they ready for this next great challenge? The guys discuss all that and more in Episode 21 of the Bills Wire podcast, which is powered by the USA Today Sports Media Group with sports betting advice for the NFL playoffs from the Sportsbook Wire.

The Bills advanced past the Colts on wild-card weekend. That’s the good news. The bad is that those hoping to avoid red-hot Baltimore in the second round of the playoffs had their dreams dashed by upset-minded Cleveland. The Browns’ win over Pittsburgh sends the Ravens to Buffalo for a can’t-miss second-round playoff game. Can the Bills slow down Lamar Jackson and a Ravens team that hasn’t lost in six games? Can Josh Allen continue to play at an elite level after securing his first playoff win as a starter. The guys tackle all that and more in anticipation for Saturday night’s epic showdown. Episode 20 of the Bills Wire podcast is powered by the USA Today Sports Media Group, with sports betting advice for the NFL playoffs from the Sportsbook Wire.

After hanging 56 points on the Dolphins and winning their sixth straight game, the Bills are playing their best football at the perfect time entering an intriguing playoff matchup with the Colts. The guys break down the matchup, and discuss the Bills’ chances of making a Super Bowl run. With odds at +700 to win the title, the Bills could be a great value bet. Episode 19 of the Bills Wire podcast is powered by the USA Today Sports Media Group, with sports betting advice for the NFL playoffs from the Sportsbook Wire.

The Bills turned Mile High into their own AFC East title celebration after pummeling the Broncos. Bills fans are reveling in their team’s first division crown since 1995. It might not be long until all of America hops on the bandwagon. The guys give their takes on the division-champ Bills, and the team’s sudden path to the No. 2 seed in the AFC playoff picture. Episode 17 of the Bills Wire podcast is powered by the USA Today Sports Media Group, with a fantasy segment from The Huddle and sports betting advice from the Sportsbook Wire.

After winning last week’s showdown with the Steelers in convincing fashion, the Bills are in position to lock up the AFC East crown for the first time since 1995. With Josh Allen playing MVP-caliber football and the defense rounding back into form, the Bills have joined the Chiefs as a legit AFC championship contender. Host Ryan O’Leary and Bills Wire editor Nick Wojton break down Sunday’s marquee win and discuss what could come next for the red-hot Bills. Episode 16 of the Bills Wire podcast is powered by the USA Today Sports Media Group, with a fantasy segment from The Huddle and sports betting advice from the Sportsbook Wire.

Josh Allen’s latest gem in a national TV spot helped the Bills score their first Monday Night Football win since the millennium. At 9-3, the Bills are poised to win their first AFC East title since 1995. Host Ryan O’Leary and Bills Wire editor Nick Wojton discuss Allen’s monster day against the 49ers and gauge the team’s chances at making a run at the Super Bowl. The guys also preview this week’s show down with the Steelers. Episode 15 of the Bills Wire Podcast is powered by USA TODAY Sports and includes fantasy football smart plays from The Huddle.com, and sports betting advice from USA TODAY Sportsbook Wire.

Host Ryan O’Leary and Bills Wire editor Nick Wojton welcome in a special guest: Matt Johnson of the Wagon Wheel and The 2-Pt Conversation podcasts. The guys wrap up Bills-Chargers, discuss Brian Daboll’s future and look ahead to Buffalo’s Week 13 matchup against the 49ers at a neutral site in Arizona. Episode 14 of the Bills Wire Podcast is powered by USA TODAY Sports and includes fantasy football smart plays from The Huddle.com, and sports betting advice from USA TODAY Sportsbook Wire.

While the Bills were home for their Week 11 bye, the Dolphins and Patriots both lost. The path to an AFC East title and top-four seed in the playoffs couldn’t be more clear. Host Ryan O’Leary and Bills Wire editor Nick Wojton discuss Buffalo’s six remaining games and look ahead to what could be a tougher matchup than most expect against the Chargers and Offensive Rookie of the Year favorite Justin Herbert. This podcast is powered by USA Today Sports and includes fantasy picks of the week from The Huddle, and sports betting advice from the Sportsbook Wire.

The Bills came a last-second heave from Kyler Murray to DeAndre Hopkins from improving to 8-2. Host Ryan O’Leary and Bills Wire editor Nick Wojton discuss what was a brutal defeat in Arizona, and what it means in Buffalo’s quest to win the AFC East. Nick also shares his favorite Bills finishes, weather games and feel-good stories of the past couple decades. This podcast is powered by USA Today Sports and includes fantasy advice from The Huddle, as well as a sports betting pick of the week from The Sportsbook Wire.

At 7-2, the Bills are in full control of the AFC East, with really only the Dolphins (5-3) to worry about. QB Josh Allen has also reentered the MVP discussion after outplaying Russell Wilson in Buffalo’s 44-34 win over the Seahawks. Host Ryan O’Leary and Bills Wire editor Nick Wojton discuss while also breaking down another fun matchup that’s on tap between the Bills and Arizona Cardinals. Powered by USA TODAY Sports with fantasy advice from The Huddle and the sports betting pick of the week from The Sportsbook Wire.

Sean McDermott, Josh Allen and the Buffalo Bills are finally celebrating a win over the Patriots. What it all means for the Bills, and are these Patriots cooked?

If not now, when? The Bills are 5-2. The Patriots are 2-4 and have managed only 18 total points in their last two games (both losses). The stage is set for coach Sean McDermott and quarterback Josh Allen to beat Belichick for the first time. A win at home Sunday buries the Patriots. A loss puts them right back into the mix. Ryan O'Leary and Bills Wire editor Nick Wojton discuss, with fantasy football advice from The Huddle, and sports betting picks from the Sportsbook Wire.

The Bills lost their second straight game to an AFC contender, this time at home to the defending Super Bowl champion Chiefs, 26-17. Some national pundits are already writing these Bills off. Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss. With Week 7 fantasy football advice from USA TODAY's The Huddle, and the pick of the week from the Sportsbook Wire.

The NFL's first Tuesday night game since Dec. 28, 2010 was not kind to the Buffalo Bills, who got trucked by the Titans — both literally and figuratively — in a 42-16 loss, their first of the season. Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss went wrong and where the Bills go from here. (With fantasy football advice from The Huddle, and sports betting tips of the week from The Sportsbook Wire.)

When Josh Allen disappeared to the locker room with a left shoulder injury, Bills Mafia held its collective breath. He really is an MVP candidate this year. These 4-0 Bills would be lost without him. Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss in Episode 6 of the Bills Wire Podcast.