If not now, when? The Bills are 5-2. The Patriots are 2-4 and have managed only 18 total points in their last two games (both losses). The stage is set for coach Sean McDermott and quarterback Josh Allen to beat Belichick for the first time. A win at home Sunday buries the Patriots. A loss puts them right back into the mix. Ryan O'Leary and Bills Wire editor Nick Wojton discuss, with fantasy football advice from The Huddle, and sports betting picks from the Sportsbook Wire.

<p>If not now, when? The Bills are 5-2. The Patriots are 2-4 and have managed only 18 total points in their last two games (both losses). The stage is set for coach Sean McDermott and quarterback Josh Allen to beat Belichick for the first time. A win at home Sunday buries the Patriots. A loss puts them right back into the mix. Ryan O'Leary and Bills Wire editor Nick Wojton discuss, with fantasy football advice from The Huddle, and sports betting picks from the Sportsbook Wire.</p>

Weekly NFL podcast covering the Buffalo Bills from USA Today Sports and BillsWire.

<p>Weekly NFL podcast covering the Buffalo Bills from USA Today Sports and BillsWire.</p>

Bills Wire Podcast

Bills Wire

Bills have chance to bury nemesis Bill Belichick and the Patriots