NFL Week 4 is here, and Todd Fuhrman and Payne Insider are breaking down eight of the biggest games on the board with picks, betting analysis, matchup advantages and the latest market movement.

The guys start with Thursday Night Football between the Pittsburgh Steelers and Cleveland Browns, examining Deshaun Watson's tendency to hold the football, Pittsburgh's dangerous pass rush and an Aaron Rodgers-led Steelers offense that showed signs of breaking out last week. 

Then it's a deep dive into the rest of the Week 4 slate, including Colts-Commanders, Cowboys-Texans, Jaguars-Bengals and Rams-Eagles. Can Joe Burrow expose a Jacksonville defense facing its first major offensive test? Are the Eagles' early-season offensive struggles a legitimate reason for concern? And can Sean McVay and the Rams take advantage of Philadelphia's defensive weaknesses? 

Plus, Todd and Payne analyze Broncos-49ers, Chiefs-Raiders and more while identifying the injuries, advanced metrics, matchup edges and betting-market moves that could define NFL Week 4.