Molecular Therapy Editor-in-Chief Dr. Joseph Glorioso joins researchers Kathy Steece-Collier (Michigan State University), Jeffrey Kordower (Arizona State University), and Fredric Manfredsson (Barrow Neurological Institute) to discuss their groundbreaking work on RNA interference for Parkinson’s disease. This episode focuses on their recent article titled "Disease-modifying, multidimensional efficacy of putaminal CaV1.3-shRNA gene therapy in aged parkinsonism male and female macaques."

Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.au

Molecular Therapy Editor-in-Chief Dr. Joseph Glorioso joins researchers Kathy Steece-Collier (Michigan State University), Jeffrey Kordower (Arizona State University), and Fredric Manfredsson (Barrow Neurological Institute) to discuss their groundbreaking work on RNA interference for Parkinson&rsquo;s disease. This episode focuses on their recent article titled "Disease-modifying, multidimensional efficacy of putaminal CaV1.3-shRNA gene therapy in aged parkinsonism male and female macaques."
Music:&nbsp;'Electric Dreams' by Scott Buckley - released under CC-BY 4.0.&nbsp;<a href="https://www.scottbuckley.com.au/">www.scottbuckley.com.au</a>

The American Society of Gene & Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

The American Society of Gene &amp; Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

ASGCT Podcast Network

RNA interference gene therapy for Parkinson’s disease with Kathy Steece-Collier, Jeffrey Kordower, and Fredric Manfredsson

In this episode of The Issue, new co-hosts Jason West, PhD, and Sanjay D’Souza, PhD, turn the mics on themselves to introduce one another to listeners. Recorded live at the ASGCT 2026 Annual Meeting in Boston, this episode invites listeners to get to know the new co-hosts as they share their backgrounds, ask each other questions, and share how listeners can get involved with future content of The Issue podcast.

Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/

In this episode of The Issue, new co-hosts Jason West, PhD, and Sanjay D&rsquo;Souza, PhD, turn the mics on themselves to introduce one another to listeners. Recorded live at the ASGCT 2026 Annual Meeting in Boston, this episode invites listeners to get to know the new co-hosts as they share their backgrounds, ask each other questions, and share how listeners can get involved with future content of The Issue podcast.
Music:&nbsp;&lsquo;Bright New Morning&rsquo; by Steven O&rsquo;Brien &ndash; released under CC-BY 4.0.&nbsp;<a href="https://www.steven-obrien.net/">https://www.steven-obrien.net/</a>

Setting the Stage: Meet the New Voices Behind The Issue

Recorded on site at the ASGCT 2026 Annual Meeting in Boston, this mini-series introduces listeners to ASGCT members and the work driving progress across the cell and gene therapy field. In each episode, members are invited to share their backgrounds, discuss the current state of the field, and reflect on the value of ASGCT membership. This series of brief, engaging conversations will help listeners get to know the people, perspectives, and ideas shaping the ASGCT community.

In this episode, host Ben McLeod of the ASGCT Communications Committee talks with Dylan Bechtle, Director of Regulatory Policy in North America at Johnson & Johnson. Dylan shares how ASGCT membership has been valuable to his career in the regulatory space, both through its community and its resources for staying up to date with the CGT field.

Music: 'Origami' by Scott Buckley – released under CC-BY 4.0. www.scottbuckley.com.au

Recorded on site at the ASGCT 2026 Annual Meeting in Boston, this mini-series introduces listeners to ASGCT members and the work driving progress across the cell and gene therapy field. In each episode, members are invited to share their backgrounds, discuss the current state of the field, and reflect on the value of ASGCT membership. This series of brief, engaging conversations will help listeners get to know the people, perspectives, and ideas shaping the ASGCT community.
In this episode, host Ben McLeod of the ASGCT Communications Committee talks with Dylan Bechtle, Director of Regulatory Policy in North America at Johnson &amp; Johnson. Dylan shares how ASGCT membership has been valuable to his career in the regulatory space, both through its community and its resources for staying up to date with the CGT field.
Music:&nbsp;'Origami' by Scott Buckley &ndash; released under CC-BY 4.0.&nbsp;<a href="https://url.us.m.mimecastprotect.com/s/IkczCERmXJSyRj4iNfxU7G5vB">www.scottbuckley.com.au</a>

Member Minutes: Dylan Bechtle

In this episode, recorded on-site at the ASGCT 2026 Annual Meeting, Molecular Therapy Advances Associate Editor-in-Chief Dr. Dan Stone speaks with Dr. Dan DuBreuil of Sanofi. They break down the science behind a recent paper detailing the development of a secretable frataxin, highlighting its potential to improve treatment efficacy for Friedreich’s ataxia.

Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.au

In this episode, recorded on-site at the ASGCT 2026 Annual Meeting, Molecular Therapy Advances Associate Editor-in-Chief Dr. Dan Stone speaks with Dr. Dan DuBreuil of Sanofi. They break down the science behind a recent paper detailing the development of a secretable frataxin, highlighting its potential to improve treatment efficacy for Friedreich&rsquo;s ataxia.
Music:&nbsp;'Electric Dreams' by Scott Buckley - released under CC-BY 4.0.&nbsp;<a href="https://www.scottbuckley.com.au/">www.scottbuckley.com.au</a>

RNA interference gene therapy for Parkinson’s disease with Kathy Steece-Collier, Jeffrey Kordower, and Fredric Manfredsson

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