Democratic candidate, Kamala Harris, is hoping to make history, by becoming not just the first female US president, but also the first black female president.
She spent the final day of campaigning in Pennsylvania, which many believe holds the keys to the White House.
Her rival, Donald Trump, campaigned in North Carolina, Pennsylvania and Michigan.
But polls suggest nationally the two are tied, as the country heads into the election.
Nick Harper reports from Washington.
Channel Africa's Mabu Boloka spoke to Professor Kealeboga Maphunye, Professor of African Politics, at the University of South Africa (UNISA)'s Department of Political Sciences and Fulbright Scholar-In-Residence, Department of Political Science, Lincoln University, Pennsylvania, USA.